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[17] demonstrated that both the lipophilic extract of Fridericia chica leaves (200 mg/mL) and one of its isolated components (carajurine) at a concentration of 500 µM had the ability to completely inhibit nuclear factor kappa B (NF-κB), which is responsible for the transcription of genes that encode several pro-inflammatory mediators and which participates in the pathogenesis of diseases such as multiple sclerosis [131,132,133]
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